"I hope our work will lead to drugs for our patients that help the immune system’s ability to recognize and eliminate cancer."
In cancer, dendritic cells (DCs) can tell T cells either to tolerate or attack tumor cells. To understand what determines this decision, Dr. Anandasabapathy is exploring which DC genes suppress anti-cancer immunity. She has already identified one that regulates tumor immunity. High expression of this gene promotes tolerance, and when...