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Meet the Honoree: Dr. Anandasabapathy

Meet the Honoree: Dr. Anandasabapathy

Immunotherapy unleashes the immune system to fight cancer, but it doesn’t work for all patients, and newly reported research may help to explain why. The study, headed by a team at Weill Cornell Medicine, indicates that the genetic program of T lymphocyte immune cells infiltrating malignant tumors, and the developmental path that these T cells then follow, may affect their response to immunotherapy and predict overall patient survival....

Vaccine development has traditionally focused on targeting antigen to skin dendritic cells (DCs), which are thought to migrate to lymph nodes to initiate an immune response. However, new research suggests that these migratory skin DCs actually have an inhibitory role and instead that it is lymphoid-resident classical DCs (cDCs) activated by FMS-like tyrosine kinase 3 ligand (FLT3L) that drive vaccination-triggered immune responses....

Weill Cornell Medicine Anandasabapathy Lab 413 E 69th St., Rm 920 New York, NY 10021 Phone: 646-962-9970